White matter microstructural changes in adolescent anorexia nervosa including an exploratory longitudinal study
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چکیده
منابع مشابه
White matter microstructural changes in adolescent anorexia nervosa including an exploratory longitudinal study
BACKGROUND Anorexia nervosa (AN) often begins in adolescence, however, the understanding of the underlying pathophysiology at this developmentally important age is scarce, impeding early interventions. We used diffusion tensor imaging (DTI) to investigate microstructural white matter (WM) brain changes including an experimental longitudinal follow-up. METHODS We acquired whole brain diffusion...
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Anorexia nervosa (AN) is a serious eating disorder that typically emerges during adolescence and occurs most frequently in females. To date, very few studies have investigated the possible impact of AN on white matter tissue properties during adolescence, when white matter is still developing. The present study evaluated white matter tissue properties in adolescent girls with AN using diffusion...
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Background. Impairments of neurocognitive performance in patients with anorexia nervosa (AN) have been reported in many studies, but no consensus has been reached. The purpose of our study was to develop a neuropsychological profile of adolescent AN patients and to determine whether or not the neuropsychological deficits are reversible with weight gain. Material and methods. 23 female AN patien...
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BACKGROUND Alzheimer's disease (AD) is a progressive neurodegenerative disorder. Current avenues of AD research focus on pre-symptomatic biomarkers that will assist with early diagnosis of AD. The majority of magnetic resonance imaging (MRI) based biomarker research to date has focused on neuronal loss in grey matter and there is a paucity of research on white matter. METHODS Longitudinal DTI...
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A massive but reversible reduction of cortical thickness and subcortical gray matter (GM) volumes in Anorexia Nervosa (AN) has been recently reported. However, the literature on alterations in white matter (WM) volume and microstructure changes in both acutely underweight AN (acAN) and after recovery (recAN) is sparse and results are inconclusive. Here, T1-weighted and diffusion-weighted MRI da...
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ژورنال
عنوان ژورنال: NeuroImage: Clinical
سال: 2016
ISSN: 2213-1582
DOI: 10.1016/j.nicl.2016.04.002